 |  AdministrationThere are two types of injectable gonadotropins available. One type is derived from human urine, while the other type is manufactured using a recombinant technique. The urinary products include products containing both luteinizing hormone (LH) and follicle-stimulating hormone (FSH), and also products that contain principally FSH with only trace amounts of LH. LH and FSH are the hormones that the pituitary normally produces and releases to stimulate the follicles developing within the ovary. The use of injectable gonadotropins gives doctors control over the amount and duration of FSH stimulation being provided to the developing follicles. Thus, it is possible to attain levels that are sufficient to stimulate development of the follicles, maturation of the egg (oocytes), and ovulation in a majority of women. Treating anovulation & oligoovulationIf you do not ovulate (anovulation) or if you ovulate irregularly (oligoovulation), the goal would be to provide you with enough FSH to stimulate the development of a single follicle. There are several ways to do this. Some women (especially those who
don’t ovulate and have a very large number of small follicles) may respond best to relatively low doses of fertility medications given over prolonged periods of time (up to several weeks). In contrast, other women may require higher doses of injectable gonadotropins to achieve adequate ovarian responsiveness, but will typically require the medication for less time (approximately 7 to 12 days). In either case it is not always possible to achieve the goal of having a single follicle develop. At times these women may have several follicles mature and release several eggs. Conception following the release of several eggs leads to a high
incidence of multiple pregnancies. For Controlled Ovarian Hyperstimulation (COH) for Assisted Reproductive Technologies (ART)If you have normal ovulatory cycles and are undergoing superovulation (the production of many mature eggs in one menstrual cycle, usually triggered by a medication that stimulates the ovaries) you may be given injectable gonadotropins. The goal of this
treatment is to interfere with a "normal" ovulatory cycle in which a single egg is released. With injectable gonadotropins, FSH levels are elevated, and this results in the stimulation of multiple eggs. Women undergoing controlled ovarian hyperstimulation (COH) for assisted reproductive technologies (ART) typically receive higher doses of injectable gonadotropins. This type of ovulation induction cycle is commonly used during insemination cycles, and
is an important part of many of the assisted reproductive technologies (ART). Related Links |
|
© 2008 Organon USA Inc. All Rights Reserved