How Follistim® AQ Vial works

Follistim® AQ Vial contains follitropin beta, which acts like naturally produced follicle-stimulating hormone (FSH), the hormone that stimulates the ovaries. It binds to the surface of the immature follicle to trigger a series of events that lead to the growth of the follicle and the maturation of the egg.

Although follitropin beta in the Follistim® AQ Vial causes the follicles to mature, it does not induce ovulation. For ovulation to occur, a second hormone called Pregnyl® (chorionic gonadotropin for injection, USP) is administered. Pregnyl® acts like luteinizing hormone (LH). It induces ovulation and releases the mature egg from the follicle.

How is Follistim® AQ Vial administered?

Follistim® AQ Vial is administered by an injection under the skin (subcutaneous injection) or into a muscle (intramuscular injection) using a conventional syringe needle. Follow the instructions given to you by your healthcare provider to give yourself an injection.

Safety information:

- Follistim® AQ Vial, like all gonadotropins, is a potent substance capable of causing mild to severe side effects including ovarian hyperstimulation syndrome (OHSS), with or without pulmonary or vascular complications.

- Follistim® AQ Vial should be prescribed only by physicians who are experienced in infertility treatment. Physicians should advise their patients of treatment risks, including OHSS and multiple births.

- Always follow your doctor’s dosing instructions when administering Follistim® AQ. Your doctor has individualized the dose to be administered based on your medical history. Do not change your dose unless instructed by your doctor.

Please see accompanying Physician Prescribing Information.